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In addition, the severity of SZ episodes might have been from the the amount regarding bed otherwise circadian rhythm interruption 143,144,145

In addition, the severity of SZ episodes might have been from the the amount regarding bed otherwise circadian rhythm interruption 143,144,145 Circadian interruption by the sleep deprivation can cause a good manic-including phenotype into the mice (increased aggression and you will hyperlocomotion), but really these effects try transient and you may behavior go back to standard within this twenty four h 136 . Knowledge on the circadian disturbance inside ICR rats, from the inverting the brand

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